Inferences of actinobacterial metabolites to combat Corona virus

The entire globe is reeling under the magnitude of current corona virus pandemic. This menace has proposed severe health and economic threats for all, thereby challenging our human existence itself. Since its outbreak, it raised concern imperative need developing novel effective agents to combat viral diseases now variants as well. Despite sincere concerted efforts scientists pharma giants all over world, there seems be no ideal recourse found till date. Natural products are rich sources compounds used in treatment infectious non-infectious diseases. There reports on natural from microbes, plants marine organisms that active against targets. Actinobacteria, largest phylum bacterial kingdom, known secondary metabolite production with diverse bioactive potentials. Nearly 65% antibiotics medicine contributed by Actinobacteria. Compared antibacterial antifungal agents, antiviral Actinobacteria less studied. In recent years studied/extreme ecosystems explored their properties. Ivermectin teicoplanin examples Actinobacteria-derived drugs available commercial use. review highlights importance actinobacteria future drug discovery.